Rotokan: instructions for use

Most people experience infectious and inflammatory diseases of the mouth, upper respiratory tract and the gastrointestinal tract. However, there are few drugs on the pharmaceutical market that do not cause any side effects. One of these medicines is Rotocan, an alcoholic extract from plant materials. The drug can be used topically, orally and rectally.

Developed for the drug Rotokan, the instructions for use describe important features, depending on the method of application and the nature of the disease.

Composition and release form

Rotokan is a liquid water-alcoholic extract from the herbal components: marigold calendula, chamomile flowers and yarrow herb in a ratio of 1: 2: 1. Available in bottles of 25, 50 or 100 ml. Packed in a carton box. It is a dark brown liquid with an unpleasant odor.

Rotokan

The drug is available in dark bottles in volumes of 25, 50 and 100 ml

pharmachologic effect

The main effect of the drug is anti-inflammatory. It is provided due to the content of chamomile substances - azulene and luteolin. Azulen activates the production of adenocorticotropic hormone, blocks the synthesis of serotonin and histamine, helps reduce the severity of pericapillary edema and reduces the vascular permeability of the microvasculature. Luteolin blocks the release of arachidonic acid and prostaglandins, which are the trigger factors for inflammation.

Rotokan also has effects:

  1. Antiseptic. Achieved through ethyl alcohol and chamomile flowers. These components destroy the cell wall of most gram-positive bacteria and lead to their subsequent death.
  2. Regenerative. Rotokan components accelerate the recovery of epithelial cells of mucous membranes. Lesions, including ulcerative defects, according to large studies, epithelialize 30% faster.
  3. Antispasmodic. All described herbs have a sedative effect. Against the background of general relaxation, the tone of smooth muscles of internal organs decreases. The apigenin contained in chamomile has a direct M-anticholinergic action. As a result, part of the efferent nerve fiber synapses are turned off and smooth myocytes relax.
  4. Hemostatic. The drug increases the tone of small peripheral vessels and contributes not only to reduce permeability, but also to stop bleeding. Ineffective with massive blood loss.
  5. Anesthetic. Achieved by antispasmodic, anti-inflammatory and antiseptic effects. Reduction of edema and the creation of conditions unsuitable for reproduction of pathogenic bacterial flora eliminate the cause of pain.

Indications for use

Rotokan is widely used in various fields of medicine as part of a combination therapy, as it potentiates the action of many medications. Motonerapiya drug is not effective. In gastroenterology, it is indicated for the treatment of pathologies such as:

  1. Gastritis.
  2. Gastroduodenitis.
  3. Peptic ulcer and duodenal ulcer.
  4. Gastroesophageal reflux.
  5. Esophagitis.
  6. Enteritis. Only chronic forms of bacterial or autoimmune etiology.
  7. Chronic colitis.
  8. Crohn's disease.
  9. Nonspecific ulcerative colitis.
  10. Proctitis
  11. Cholecystitis.
  12. Condition after removal of the gallbladder.

In dentistry and otolaryngology, it is used to treat the following pathologies:

  1. Aphthous stomatitis is an inflammation of the mucous membrane of the oral cavity with a lot of ulcers.
  2. Ulcerative-necrotic stomatitis. Only with purulent forms and complications in the form of osteomyelitis of the facial skeleton.
  3. Gingivitis.
  4. Periodontitis
  5. Preventive agent after dental surgery (tooth extraction, gum closure, etc.).
  6. Rhinitis without involvement of the paranasal sinuses.
  7. Aphthous stomatitis.
Stomatitis

For diseases of the oral cavity, including stomatitis, Rotocan is used by application or rinsing

Also recommended inhalation drug in pulmonary practice with:

  • Acute respiratory diseases of the upper respiratory tract, caused mainly by bacterial flora;
  • Chronic bronchitis (including signs of respiratory failure);
  • Interstitial pneumonia.

Contraindications

Despite the relative safety and composition of plant origin, the use of the drug is not recommended in the following situations:

  1. Hypersensitivity to the individual components of the drug. It is forbidden to use Rotokan in the presence of previously allergic reactions to ethyl alcohol, chamomile and calendula flowers, yarrow herb.
  2. Proliferative pathologies in the area of ​​contact with the drug (for tumors of the oral cavity and gastrointestinal tract it is forbidden to take the drug orally and topically). Active substances increase the activity of division of mutated cells.
  3. Any diseases of the liver and gallbladder, kidney disease with severe renal insufficiency (chronic kidney disease grade II and above), as well as glomerulonephritis and pyelonephritis. Restriction is imposed only on the use of medicinal enemas with Rotokan.
  4. Gestation period Yarrow herb has a stimulating effect on the ovaries. As a result, increased estrogen production. Hyperestrogenic background interferes with the normal development of the child (large fetus, anomalies and malformations), worsens the general condition of the mother (contributes to nausea and vomiting, edema, the development of pre-eclampsia) and adversely affects the upcoming childbirth bleeding, premature detachment of a normally located placenta). Ethanol has a pronounced direct teratogenic effect: a change in facial features (small head, flat face, transformation of the architectonics of the head section of the skeleton), congenital defects (from the skeleton, cardiovascular and urinary systems, organ of vision). 10 ml of pure ethanol can provoke premature onset of labor, stunting of the fetus, miscarriage. Sedative and antispasmodic effects reduce the tone of the uterus, increase the risk of premature disclosure of the cervix and the weakness of labor during childbirth.
  5. Breast-feeding. Ethanol can be ingested through breast milk. In order to avoid alcohol intoxication, the development of dependence and toxic effects on the organs of the newborn during lactation, Rotocan cannot be used.

It is important! For external use of the drug during pregnancy or lactation is recommended to consult with your doctor.

Pregnancy

Rotokan contains ethanol in its composition, because during pregnancy the solution can be used only after consulting with your doctor

The drug is completely contraindicated in children under 13 years due to the possible high allergic activity.

Side effects

In most cases (99.9%) the drug is well tolerated.All undesirable reactions are associated with immediate-type hypersensitivity and can manifest themselves in the form of the following conditions:

  1. Urticaria - the rapid development of a rash with papular rash on the entire surface of the skin. After 30-120 minutes from the onset of the disease, the papules are replaced by blisters with transparent contents that are prone to fusion. May affect mucous membranes. Usually passes independently within 24 hours.
  2. Isolated pruritus. It is characterized by itching on limited areas of the skin (in 80% of cases) or on the entire surface of the body. Damage caused by the brush may become infected.
  3. Anaphylactic shock - a rapid (within 5–15 minutes) decrease in the tone of large vessels, leading to a decrease in the overall peripheral resistance and a drop in blood pressure. The person quickly loses consciousness, the heart rate rises, breathing can be disturbed (often superficial or pathological, for example, Cheyne-Stokes). Externally, the skin is pale with a marble shade and a large amount of cold sticky sweat, there is acrocyanosis. Multi-organ failure is rapidly growing against the background of hypoxia of all tissues.
  4. Angioedema (angioedema) - the development of edema of tissues that have developed subcutaneous fat. In typical cases, the eyelids, lips, neck are affected. It can spread to the mucous membrane of the larynx and cause respiratory failure due to obstruction of the lumen of the respiratory tract. The condition deteriorates sharply (noisy breathing, the face turns blue), and hypercapnic coma can occur, and then death.
Hives

Rotokan, as a plant product, can only lead to one side effect - an allergic reaction that can manifest itself in the form of, for example, urticaria

It is important! With the development of any allergic reaction is an urgent need to stop using the drug. The appearance of clinical signs of angioedema or anaphylactic shock requires an emergency call for emergency medical assistance.

First aid for the development of adverse reactions

If symptoms of urticaria occur,

  1. Take antihistamines second and third generation. Loratadine or Cetiresin will do. Both drugs block the H1-histamine receptors, which leads to the cessation of the release of histamine, causing edema, hypersecretion of mucus and smooth muscle spasm. Loratadin taken 1 tablet (0.01) per day, orally. Cetiresin - 1 tablet (0,005) 1 time per day inside. The duration of further treatment is at least 30 days.
  2. Provide complete rest.
  3. Assign a hypoallergenic diet with the exception of the diet of spicy, fried foods, spices, citrus, coffee and cocoa, dairy products, any fruits and vegetables that have a bright red or orange color (red apples, radishes, tomatoes, etc.).
Allergenic Products

At the first symptoms of an allergic reaction, allergenic products should be removed from the diet.

With a rise in body temperature, a drop in blood pressure, arthralgia, an urgent need to consult a doctor.

With anaphylactic shock:

  1. Rinse the mucous membranes of the mouth or nose with running water and drip a few drops of 1% adrenaline solution into the nose and throat. You can use any drops containing adrenomimetics (for example, Xylene - drops for the treatment of rhinitis).
  2. If the solution got into the stomach, then you need to immediately wash it and take any absorbent. For example, activated carbon (1 tablet for every 10 kg of body weight).
  3. Lay the patient on his side. It is desirable that the legs were above the level of the upper half of the body. Turn your head to the side and push the lower jaw.
  4. Provide fresh air.
  5. To warm the patient, having enclosed warmers with warm water.

In parallel with the provision of first aid, a team of doctors must be called. Further treatment will take place in the intensive care unit.

When Quincke is swollen, the help algorithm is somewhat different:

  1. Wash the mucous membranes of the nose or mouth with plenty of water. Similarly, drip 1% andrenaline solution.
  2. If the solution gets into the stomach, use adsorbent - activated charcoal.
  3. Seat the patient, remove the outerwear or unbutton it. This is necessary for maximum relief of breathing.
  4. Provide fresh air.

It is necessary to urgently call an ambulance. The patient is sent to the intensive care unit and intensive care.

It is important! It is impossible to wash the stomach against Quincke's edema! With increasing swelling of the upper respiratory tract, the patient may choke on their own vomitus.

Dosage and administration

The drug can be used in various ways:

  • Locally;
  • Orally;
  • Rectally.

Each route of administration has its own specific features. Concentrated solution is not recommended to use, it is necessary to dilute it with pure distilled or boiled water.

Gargle

For the treatment of angina or tonsillitis 1 tsp. (5 ml) of the drug is dissolved in 200 ml (1 cup) of warm water. If the drug is well tolerated, the concentration can be increased to 2-3 tsp. on 200 ml of liquid. The ideal water temperature is about 40-45 degrees.

Sore throat

The drug has found widespread use in angina, pharyngitis and tonsillitis.

The resulting solution is necessary to rinse the mouth for 2-3 minutes, 3-5 times a day. After irrigation of the throat, it is recommended not to eat food for 30 minutes.

With dental diseases

In the dental practice, the concentration of the solution is similar (1 tsp per 200 ml of warm water).

For stomatitis and other infectious-inflammatory diseases of the oral cavity formations in a Rotokan solution, cotton or gauze swabs are moistened and applied in the form of appliqués on the affected areas. Duration - about 20-25 minutes. After which the tampon is removed. The duration of treatment is up to 7 days, 3-4 applications per day.

With periodontitis, after the destruction of tartar or plaque, scraping pockets between the gum and the tooth, tampons impregnated with the treatment solution are inserted under the gum for 25-30 minutes. You need to perform 6 procedures for 6 days (1 time per day).

For ingestion and rectal

In diseases of the upper gastrointestinal tract (above the level of the duodenum), Rotocan is administered orally. It is necessary to use 80-130 ml of solution (1 tsp per 200 ml of water) 2-4 times per day. The total duration of treatment is not more than 10 days.

At statement microclysm 1 h. Rotokan diluted in 70-100 ml. warm boiled water. Staging produce 1-2 times a day after bowel movements (natural bowel movement). The maximum duration of the course of therapy is up to 20 days.

For inhalation using a nebulizer

For inhalation procedures suitable compression or ultrasonic nebulizer.

Using a nebulizer

The principle of operation of the nebulizer is based on dispersed spraying of the drug, which is fed through a mask into the throat

To prepare a medicinal solution with a concentration of 1:20 need to dilute 1 tsp. Rotocan in 100 ml of saline - NaCl 0.9%. After filling the flask (3-4 ml of the medicinal product) and placing it in the nebulizer, you need to put on a mask and inhale deeply the supplied air with a lot of small vapor particles until the end of the solution (about 10 minutes).

The therapeutic dose for this method is 12 ml divided into 3 procedures.

Overdose

With the observance of therapeutic doses and the choice of the correct method of application of symptoms of overdose is not registered. With a significant excess therapeutic dose (more than 15-20 times) may appear:

  • Dizziness;
  • Diffuse headaches;
  • Dyspeptic disorders (pain and feeling of heaviness in the epigastric region, heartburn);
  • Nausea and vomiting.

When ingestion of more than 30 ml of Rotokan, signs of myocardial ischemia appear due to significant activation of the heart.Clinically, this is manifested by a feeling of pressure and pain behind the sternum, which increases with any physical activity.

Treatment is symptomatic. For headaches, take any non-narcotic analgesic (non-steroidal anti-inflammatory agent). For example, 1 tablet of Nurofen.

For disorders of the gastrointestinal tract, it is recommended to wash the stomach, then take the adsorbent - activated charcoal (1 tablet for every 10 kg of body weight, once). If after emptying the stomach vomiting does not stop, you should use Metoclopramide. Dosage - 1 tablet (0.01) 3 times a day. With the disappearance of nausea reception stops

Activated carbon

In case of violations of the gastrointestinal tract, you must wash the stomach, and then take a few tablets of activated carbon

If there are symptoms of severe heartburn, you must take an adsorbing and antacid. Phosphalugel can be used (1 sachet, by mouth, once) or Gastal (1 tablet for resorption, once).

It is important! If any clinical manifestation of an overdose of the drug develops, you should consult a doctor to find out the exact cause of the onset of symptoms and determine the extent of the disorder. With the development of signs of myocardial ischemia, it is necessary to lay down the patient, ensuring complete rest, and call the ambulance brigade.

Terms and conditions of storage

Rotokan is stored in a cool place (10-12aboutC), protected from direct sunlight. The location of the drug should be protected from children.

Shelf life - up to 2 years from the date of production. The date of manufacture is indicated on the packaging. After opening Rotokan must be used within 10 days.

Price

The average cost of the drug in pharmacies varies by region.

Vial volumeCost of
25 ml25-30 rub.
50 ml50-70 rubles
100 ml90-140 rubles

Analogs

On the pharmaceutical market there are few products with a similar composition and action that are of plant origin.

Drug nameRoute of administration
JekatonLocally, orally, rectally
DentokindOrally
PhytodentLocally

Thus, Rotokan is an excellent safe drug in combination therapy used to treat various infectious and inflammatory diseases of the mucous membranes. The drug has a small number of side effects, which makes it, together with the low cost of the drug of choice for most people.

Implantation

Veneers

Crowns